Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C06048
Pert ID: BRD-K81647657
Compound Name: 3-methyladenine
Targets: PI3
MoA: PI3K inhibitor
SMILES: Cn1cnc(=N)c2nc[nH]c12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8993 BRD-K81647657 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9118 BRD-K81647657 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9986 BRD-K81647657 HA1E 10 uM 24 h 0.26 1.07 0.19 0.0 0.0 0.0
10356 BRD-K81647657 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10605 BRD-K81647657 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10858 BRD-K81647657 HEPG2 10 uM 6 h -0.22 -0.93 0.07 0.0 0.0 0.0
11112 BRD-K81647657 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11236 BRD-K81647657 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11586 BRD-K81647657 NCIH2073 10 uM 6 h -0.2 -0.85 0.01 0.0 0.0 0.0
11849 BRD-K81647657 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12390 BRD-K81647657 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12561 BRD-K81647657 PC3 10 uM 24 h 0.0 0.0 0.0 0.39 1.37 2.09
12878 BRD-K81647657 SW480 10 uM 6 h 0.0 0.0 0.0 -0.22 -0.73 0.05
13095 BRD-K81647657 THP1 10 uM 6 h -0.2 -0.84 0.0 0.0 0.0 0.0
13370 BRD-K81647657 U937 10 uM 6 h 0.21 0.87 0.01 -0.27 -0.9 0.28
13505 BRD-K81647657 VCAP 10 uM 24 h -0.18 -0.75 0.0 0.23 0.81 0.09
98773 BRD-K81647657 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99097 BRD-K81647657 NEU 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).