CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C06053
Pert ID:	BRD-K97118047
Compound Name:	4,5,6,7-tetrabromobenzotriazole
Targets:	AKT1\|CHEK1\|CSNK2A1\|GSK3B\|LCK\|MAP2K1\|MAPK1\|MAPK11\|MAPK12\|MAPK14\|MAPK8\|PRKCA\|ROCK1\|RPS6KB1\|SGK1
MoA:	casein kinase inhibitor
SMILES:	Brc1c(Br)c(Br)c2[nH]nnc2c1Br
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
2952	BRD-K97118047	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
3415	BRD-K97118047	HCC515	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
3996	BRD-K97118047	VCAP	10 uM	6 h	0.25	1.02	0.13	-0.41	-1.36	2.02
39865	BRD-K97118047	ASC	10 uM	24 h	0.0	0.0	0.0	0.32	1.15	0.88
40151	BRD-K97118047	HEPG2	10 uM	6 h	0.0	0.0	0.0	-0.29	-0.98	0.49
40409	BRD-K97118047	HT29	10 uM	6 h	-0.26	-1.07	0.28	-0.28	-0.94	0.36
40959	BRD-K97118047	NEU	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
41627	BRD-K97118047	SKB	10 uM	24 h	0.0	0.0	0.0	0.35	1.25	1.29
95774	BRD-K97118047	A375	25 uM	6 h	0.0	0.0	0.0	0.22	0.77	0.06
95797	BRD-K97118047	MCF??7.00	25 uM	6 h	0.0	0.0	0.0	0.37	1.3	1.49
95818	BRD-K97118047	NPC	25 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
95843	BRD-K97118047	A549	25 uM	6 h	0.0	0.0	0.0	-0.22	-0.75	0.06
95876	BRD-K97118047	PC3	25 uM	6 h	-0.18	-0.75	0.0	-0.33	-1.11	0.9
95945	BRD-K97118047	YAPC	25 uM	6 h	0.0	0.0	0.0	0.27	0.95	0.32

Summary