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CMap Candidate Details

Structure:
CMap ID: C06067
Pert ID: BRD-K25690923
Compound Name: 4-iodo-6-phenylpyrimidine
Targets: MIF
MoA: macrophage migration inhibiting factor inhibitor
SMILES: Ic1cc(ncn1)-c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8926 BRD-K25690923 A375 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9190 BRD-K25690923 A549 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9390 BRD-K25690923 AGS 40 uM 6 h 0.0 0.0 0.0 -0.27 -0.92 0.33
9702 BRD-K25690923 H1299 40 uM 6 h 0.0 0.0 0.0 0.28 0.98 0.36
9886 BRD-K25690923 HA1E 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10129 BRD-K25690923 HCC515 40 uM 24 h 0.0 0.0 0.0 0.33 1.16 0.9
10486 BRD-K25690923 HCT116 40 uM 6 h 0.0 0.0 0.0 -0.32 -1.09 0.84
10762 BRD-K25690923 HEPG2 40 uM 6 h 0.0 0.0 0.0 -0.25 -0.84 0.18
11061 BRD-K25690923 HT29 40 uM 6 h 0.0 0.0 0.0 -0.29 -0.98 0.47
11142 BRD-K25690923 MCF??7.00 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11452 BRD-K25690923 NCIH2073 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11738 BRD-K25690923 NCIH508 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12017 BRD-K25690923 NCIH596 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12600 BRD-K25690923 PC3 40 uM 6 h 0.0 0.0 0.0 0.19 0.68 0.01
12764 BRD-K25690923 SW480 40 uM 6 h -0.19 -0.79 0.0 0.0 0.0 0.0
12953 BRD-K25690923 THP1 40 uM 6 h -0.22 -0.94 0.08 0.0 0.0 0.0
13244 BRD-K25690923 U937 40 uM 6 h 0.28 1.17 0.38 0.0 0.0 0.0
13461 BRD-K25690923 VCAP 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).