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CMap Candidate Details

Structure:
CMap ID: C00609
Pert ID: BRD-K82818427
Compound Name: batimastat
Targets: ADAM28|ADAMTS5|MMP12|MMP16|MMP2|MMP8
MoA: matrix metalloprotease inhibitor
SMILES: CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)[C@H](CSc1cccs1)C(=O)NO
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8994 BRD-K82818427 A375 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9241 BRD-K82818427 A549 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9523 BRD-K82818427 AGS 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9828 BRD-K82818427 H1299 40 uM 6 h -0.28 -1.15 0.44 0.0 0.0 0.0
10085 BRD-K82818427 HA1E 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10149 BRD-K82818427 HCC515 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10861 BRD-K82818427 HEPG2 40 uM 6 h 0.29 1.2 0.43 -0.23 -0.79 0.11
11022 BRD-K82818427 HT29 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11157 BRD-K82818427 MCF??7.00 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11590 BRD-K82818427 NCIH2073 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11852 BRD-K82818427 NCIH508 40 uM 6 h 0.0 0.0 0.0 -0.43 -1.45 15.35
12148 BRD-K82818427 NCIH596 40 uM 6 h 0.24 1.0 0.1 0.0 0.0 0.0
12466 BRD-K82818427 PC3 40 uM 24 h 0.0 0.0 0.0 0.23 0.82 0.1
12881 BRD-K82818427 SW480 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12982 BRD-K82818427 THP1 40 uM 6 h 0.26 1.08 0.21 0.0 0.0 0.0
13372 BRD-K82818427 U937 40 uM 6 h -0.27 -1.12 0.38 -0.28 -0.93 0.35
13506 BRD-K82818427 VCAP 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).