CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C06091
Pert ID:	BRD-K24844714
Compound Name:	5-fluorouracil
Targets:	DPYD\|TYMS
MoA:	thymidylate synthase inhibitor
SMILES:	Fc1c[nH]c(=O)[nH]c1=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
90770	BRD-K24844714	HPTEC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
91347	BRD-K24844714	HUH7	25 uM	72 h	0.0	0.0	0.0	0.4	1.43	2.2
95627	BRD-K24844714	U2OS	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
96326	BRD-K24844714	A375	10 uM	24 h	-0.28	-1.16	0.46	-0.53	-1.78	15.65
117055	BRD-K24844714	A549	10 uM	24 h	0.0	0.0	0.0	-0.36	-1.23	1.25
117137	BRD-K24844714	HCC515	3.33 uM	24 h	0.0	0.0	0.0	-0.21	-0.69	0.03
117182	BRD-K24844714	HEPG2	10 uM	24 h	-0.22	-0.91	0.06	0.0	0.0	0.0
120913	BRD-K24844714	HA1E	10 uM	24 h	0.0	0.0	0.0	-0.31	-1.04	0.66
120960	BRD-K24844714	HEK293	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120988	BRD-K24844714	HELA	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121048	BRD-K24844714	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121116	BRD-K24844714	YAPC	10 uM	24 h	0.0	0.0	0.0	-0.33	-1.1	0.86
129194	BRD-K24844714	HT29	2.22 uM	24 h	0.0	0.0	0.0	-0.33	-1.11	0.9
129221	BRD-K24844714	PC3	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary