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CMap Candidate Details

Structure:
CMap ID: C00611
Pert ID: BRD-A18763547
Compound Name: BAX-channel-blocker
Targets: BAX
MoA: cytochrome C release inhibitor
SMILES: OC(CN1CCNCC1)Cn1c2ccc(Br)cc2c2cc(Br)ccc12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8863 BRD-A18763547 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9274 BRD-A18763547 AGS 10 uM 6 h -0.23 -0.96 0.1 0.28 1.0 0.42
9577 BRD-A18763547 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10002 BRD-A18763547 HA1E 10 uM 6 h 0.0 0.0 0.0 0.34 1.2 1.07
10278 BRD-A18763547 HCC515 10 uM 6 h 0.0 0.0 0.0 0.31 1.11 0.74
10386 BRD-A18763547 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10656 BRD-A18763547 HEPG2 10 uM 6 h 0.18 0.76 0.0 0.0 0.0 0.0
10898 BRD-A18763547 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11246 BRD-A18763547 MCF??7.00 10 uM 6 h 0.16 0.68 0.0 0.0 0.0 0.0
12193 BRD-A18763547 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12577 BRD-A18763547 PC3 10 uM 6 h -0.32 -1.32 0.83 0.0 0.0 0.0
12653 BRD-A18763547 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12976 BRD-A18763547 THP1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13525 BRD-A18763547 VCAP 10 uM 6 h 0.32 1.34 0.89 0.0 0.0 0.0
90563 BRD-A18763547 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).