CMap Candidate Details
Structure:
| CMap ID: | C06112 |
| Pert ID: | BRD-K45293975 |
| Compound Name: | 7-hydroxystaurosporine |
| Targets: | CHEK1|MARK3|PDPK1 |
| MoA: | CDK inhibitor; CHK inhibitor; PKC inhibitor |
| SMILES: | CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4[C@H](O)NC(=O)c4c4c5ccccc5n2c4c13 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 90831 | BRD-K45293975 | MCF10A | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.34 | 1.21 | 1.15 |
| 97326 | BRD-K45293975 | HAP1 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 97337 | BRD-K45293975 | A375 | 0.66 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.36 | -1.21 | 1.24 |