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CMap Candidate Details

Structure:
CMap ID: C06116
Pert ID: BRD-K04430056
Compound Name: 7-nitroindazole
Targets: NOS1|NOS2|NOS3
MoA: nitric oxide synthase inhibitor
SMILES: [O-][N+](=O)c1cccc2cn[nH]c12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8900 BRD-K04430056 A375 80 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9341 BRD-K04430056 AGS 80 uM 6 h 0.27 1.13 0.29 0.0 0.0 0.0
9647 BRD-K04430056 H1299 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10024 BRD-K04430056 HA1E 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10118 BRD-K04430056 HCC515 80 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.62
10444 BRD-K04430056 HCT116 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10715 BRD-K04430056 HEPG2 80 uM 6 h 0.2 0.85 0.01 0.0 0.0 0.0
10931 BRD-K04430056 HT29 80 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.56
11129 BRD-K04430056 MCF??7.00 80 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11397 BRD-K04430056 NCIH2073 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11697 BRD-K04430056 NCIH508 80 uM 6 h 0.23 0.96 0.07 0.18 0.64 0.0
11968 BRD-K04430056 NCIH596 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12252 BRD-K04430056 NOMO1 80 uM 6 h 0.0 0.0 0.0 -0.28 -0.93 0.36
12587 BRD-K04430056 PC3 80 uM 6 h 0.0 0.0 0.0 0.33 1.15 0.9
12713 BRD-K04430056 SW480 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12933 BRD-K04430056 THP1 80 uM 6 h -0.26 -1.07 0.27 0.0 0.0 0.0
13193 BRD-K04430056 U937 80 uM 6 h 0.16 0.67 0.0 -0.3 -1.0 0.52
13570 BRD-K04430056 VCAP 80 uM 6 h -0.24 -0.99 0.14 0.0 0.0 0.0
22233 BRD-K04430056 A549 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.93 0.35
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).