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CMap Candidate Details

Structure:
CMap ID: C00612
Pert ID: BRD-A05457250
Compound Name: BAY-K-8644-(+/-)
Targets:
MoA: L-type calcium channel activator
SMILES: COC(=O)C1=C(C)NC(C)=C(C1c1ccccc1C(F)(F)F)[N+]([O-])=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
98964 BRD-A05457250 NEU 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
99194 BRD-A05457250 NPC 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
127741 BRD-A05457250 A375 3.33 uM 24 h 0.0 0.0 0.0 -0.29 -0.96 0.44
127785 BRD-A05457250 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127821 BRD-A05457250 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127865 BRD-A05457250 HEK293 0.37 uM 24 h -0.24 -0.99 0.13 -0.3 -1.03 0.62
127939 BRD-A05457250 HUVEC 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127992 BRD-A05457250 MCF10A 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128050 BRD-A05457250 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135566 BRD-A05457250 HELA 2.22 uM 24 h 0.21 0.88 0.01 0.0 0.0 0.0
135612 BRD-A05457250 HT29 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135657 BRD-A05457250 JURKAT 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135695 BRD-A05457250 MCF??7.00 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135743 BRD-A05457250 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.37
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).