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CMap Candidate Details

Structure:
CMap ID: C00613
Pert ID: BRD-K14329163
Compound Name: BAY-K-8644-(s)-(-)
Targets: CACNA1C
MoA: L-type calcium channel activator
SMILES: COC(=O)C1=C(C)NC(C)=C([C@H]1c1ccccc1C(F)(F)F)[N+]([O-])=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8915 BRD-K14329163 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9086 BRD-K14329163 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9369 BRD-K14329163 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9675 BRD-K14329163 H1299 10 uM 6 h 0.28 1.18 0.38 0.19 0.66 0.01
9927 BRD-K14329163 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.24 1.35
10307 BRD-K14329163 HCC515 10 uM 6 h -0.21 -0.89 0.04 0.0 0.0 0.0
10739 BRD-K14329163 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10949 BRD-K14329163 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11267 BRD-K14329163 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11428 BRD-K14329163 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11719 BRD-K14329163 NCIH508 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.05 0.69
12273 BRD-K14329163 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12499 BRD-K14329163 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12739 BRD-K14329163 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13219 BRD-K14329163 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13587 BRD-K14329163 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).