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CMap Candidate Details

Structure:
CMap ID: C00615
Pert ID: BRD-K15025317
Compound Name: BAY-11-7082
Targets: RELA
MoA: NFkB pathway inhibitor
SMILES: Cc1ccc(cc1)S(=O)(=O)\C=C\C#N
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2839 BRD-K15025317 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9370 BRD-K15025317 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9678 BRD-K15025317 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10311 BRD-K15025317 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.19 -0.63 0.01
10468 BRD-K15025317 HCT116 10 uM 6 h -0.22 -0.91 0.05 0.0 0.0 0.0
10742 BRD-K15025317 HEPG2 10 uM 6 h -0.22 -0.9 0.04 0.0 0.0 0.0
10952 BRD-K15025317 HT29 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.12
11269 BRD-K15025317 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.35 1.25 1.29
11430 BRD-K15025317 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12594 BRD-K15025317 PC3 10 uM 6 h -0.3 -1.24 0.67 0.0 0.0 0.0
13221 BRD-K15025317 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13589 BRD-K15025317 VCAP 10 uM 6 h -0.21 -0.88 0.03 -0.28 -0.93 0.36
44870 BRD-K15025317 ASC 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.54
45985 BRD-K15025317 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46304 BRD-K15025317 PHH 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.05
96117 BRD-K15025317 A549 10 uM 24 h 0.0 0.0 0.0 -0.45 -1.53 15.35
97299 BRD-K15025317 HAP1 0.66 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97340 BRD-K15025317 A375 3.33 uM 24 h 0.0 0.0 0.0 -0.48 -1.61 15.65
100128 BRD-K15025317 U2OS 25 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).