Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C00620
Pert ID: BRD-K53281329
Compound Name: BAY-61-3606
Targets: SYK
MoA: syk inhibitor
SMILES: COc1ccc(cc1OC)-c1cc2nccn2c(Nc2ncccc2C(N)=O)n1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91812 BRD-K53281329 HS578T 10 uM 6 h -0.22 -0.91 0.05 0.0 0.0 0.0
91895 BRD-K53281329 MDAMB231 10 uM 24 h 0.23 0.95 0.06 0.0 0.0 0.0
91940 BRD-K53281329 SKBR3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94413 BRD-K53281329 A375 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94444 BRD-K53281329 A549 10 uM 24 h 0.0 0.0 0.0 0.21 0.74 0.04
94511 BRD-K53281329 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94547 BRD-K53281329 CD34 10 uM 24 h 0.24 1.02 0.13 0.0 0.0 0.0
94595 BRD-K53281329 HCC515 10 uM 24 h 0.23 0.98 0.09 -0.33 -1.11 0.91
94638 BRD-K53281329 HEK293 10 uM 24 h 0.24 1.01 0.12 0.29 1.01 0.45
94688 BRD-K53281329 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94742 BRD-K53281329 HME1 10 uM 24 h 0.27 1.13 0.3 0.0 0.0 0.0
94790 BRD-K53281329 HT29 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94834 BRD-K53281329 HUVEC 10 uM 24 h 0.33 1.36 0.97 -0.3 -0.99 0.51
94887 BRD-K53281329 JURKAT 10 uM 24 h 0.23 0.96 0.07 0.24 0.83 0.12
94933 BRD-K53281329 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94974 BRD-K53281329 MCF??7.00 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95013 BRD-K53281329 NEU 10 uM 24 h -0.22 -0.91 0.05 -0.3 -1.02 0.6
95052 BRD-K53281329 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95116 BRD-K53281329 PC3 3.33 uM 24 h -0.16 -0.68 0.0 0.0 0.0 0.0
95160 BRD-K53281329 SHSY5Y 10 uM 24 h 0.0 0.0 0.0 0.32 1.13 0.83
95207 BRD-K53281329 SKL 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95270 BRD-K53281329 THP1 3.33 uM 24 h 0.28 1.17 0.38 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).