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CMap Candidate Details

Structure:
CMap ID: C00629
Pert ID: BRD-K17008822
Compound Name: BD-1008
Targets:
MoA: sigma receptor antagonist
SMILES: CN(CCN1CCCC1)CCc1ccc(Cl)c(Cl)c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1745 BRD-K17008822 HA1E 10 uM 6 h -0.32 -1.34 0.96 0.0 0.0 0.0
1898 BRD-K17008822 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2382 BRD-K17008822 PC3 10 uM 6 h 0.24 0.98 0.09 -0.27 -0.91 0.31
2579 BRD-K17008822 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42072 BRD-K17008822 A549 10 uM 6 h 0.22 0.9 0.02 0.0 0.0 0.0
42317 BRD-K17008822 ASC 10 uM 24 h 0.25 1.05 0.16 0.38 1.34 1.72
42648 BRD-K17008822 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42951 BRD-K17008822 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43304 BRD-K17008822 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43508 BRD-K17008822 NPC 10 uM 24 h 0.0 0.0 0.0 -0.43 -1.44 15.35
43807 BRD-K17008822 PHH 10 uM 24 h 0.0 0.0 0.0 0.23 0.81 0.09
44084 BRD-K17008822 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).