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CMap Candidate Details

Structure:
CMap ID: C00635
Pert ID: BRD-K97810537
Compound Name: beclomethasone-dipropionate
Targets: GPR97|NR3C1
MoA: glucocorticoid receptor agonist
SMILES: CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]12C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3418 BRD-K97810537 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3577 BRD-K97810537 PC3 10 uM 24 h -0.23 -0.95 0.09 0.0 0.0 0.0
3914 BRD-K97810537 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39254 BRD-K97810537 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39539 BRD-K97810537 A549 10 uM 6 h -0.23 -0.94 0.08 -0.27 -0.91 0.3
39870 BRD-K97810537 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40155 BRD-K97810537 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40413 BRD-K97810537 HT29 10 uM 6 h 0.0 0.0 0.0 0.3 1.08 0.65
40674 BRD-K97810537 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40964 BRD-K97810537 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
50270 BRD-K97810537 HA1E 10 uM 6 h 0.0 0.0 0.0 0.24 0.84 0.13
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).