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CMap Candidate Details

Structure:
CMap ID: C00641
Pert ID: BRD-K14993104
Compound Name: bemegride
Targets: GABRA1
MoA: chemoreceptor agonist
SMILES: CCC1(C)CC(=O)NC(=O)C1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4066 BRD-K14993104 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.58
4373 BRD-K14993104 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.13 1.0
4900 BRD-K14993104 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44528 BRD-K14993104 A549 10 uM 24 h 0.2 0.84 0.0 0.0 0.0 0.0
44869 BRD-K14993104 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45173 BRD-K14993104 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45984 BRD-K14993104 NPC 10 uM 24 h 0.0 0.0 0.0 0.27 0.97 0.36
46303 BRD-K14993104 PHH 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.79
100127 BRD-K14993104 U2OS 12.5 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
122270 BRD-K14993104 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122448 BRD-K14993104 PC3 0.125 uM 24 h 0.21 0.87 0.01 0.0 0.0 0.0
122494 BRD-K14993104 THP1 10 uM 24 h -0.28 -1.15 0.45 0.0 0.0 0.0
130638 BRD-K14993104 HEK293 2.22 uM 24 h 0.23 0.96 0.07 0.0 0.0 0.0
130681 BRD-K14993104 HELA 0.01 uM 24 h -0.17 -0.7 0.0 -0.23 -0.77 0.08
130723 BRD-K14993104 HT29 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130747 BRD-K14993104 MCF10A 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130767 BRD-K14993104 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.2 0.7 0.02
130795 BRD-K14993104 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130847 BRD-K14993104 YAPC 0.74 uM 24 h -0.21 -0.89 0.04 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).