CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00642
Pert ID:	BRD-A85587465
Compound Name:	bemesetron
Targets:	HTR3A\|HTR3B
MoA:	serotonin receptor antagonist
SMILES:	CN1C2CCC1CC(C2)OC(=O)c1cc(Cl)cc(Cl)c1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
2823	BRD-A85587465	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
3123	BRD-A85587465	HCC515	10 uM	24 h	0.22	0.92	0.04	0.0	0.0	0.0
3707	BRD-A85587465	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
39288	BRD-A85587465	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
39603	BRD-A85587465	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
39923	BRD-A85587465	HEPG2	10 uM	6 h	0.23	0.94	0.06	0.0	0.0	0.0
40208	BRD-A85587465	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
40441	BRD-A85587465	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
40726	BRD-A85587465	NEU	10 uM	24 h	0.0	0.0	0.0	-0.34	-1.14	1.01
41028	BRD-A85587465	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
41351	BRD-A85587465	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
96324	BRD-A85587465	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
96394	BRD-A85587465	PC3	10 uM	24 h	0.0	0.0	0.0	0.29	1.04	0.55
100368	BRD-A85587465	U2OS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
136406	BRD-A85587465	SHSY5Y	0.04 uM	24 h	0.0	0.0	0.0	-0.39	-1.32	1.71

Summary