CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00646
Pert ID:	BRD-K17068645
Compound Name:	bendamustine
Targets:
MoA:	DNA inhibitor
SMILES:	Cn1c(CCCC(O)=O)nc2cc(ccc12)N(CCCl)CCCl
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
117325	BRD-K17068645	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
117405	BRD-K17068645	HA1E	10 uM	24 h	0.36	1.51	1.43	0.0	0.0	0.0
117447	BRD-K17068645	HCC515	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
117492	BRD-K17068645	HEPG2	10 uM	24 h	0.0	0.0	0.0	-0.28	-0.93	0.35
117582	BRD-K17068645	MCF??7.00	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
117620	BRD-K17068645	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120287	BRD-K17068645	A549	3.33 uM	24 h	0.0	0.0	0.0	0.2	0.7	0.01
120347	BRD-K17068645	HELA	10 uM	24 h	0.0	0.0	0.0	0.3	1.06	0.59
120483	BRD-K17068645	YAPC	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128951	BRD-K17068645	HT29	2.22 uM	24 h	0.0	0.0	0.0	-0.2	-0.66	0.01

Summary