CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00065
Pert ID:	BRD-K37814297
Compound Name:	acepromazine
Targets:	ADRA1A\|ADRA1B\|DRD1\|DRD2\|HTR1A\|HTR2A
MoA:	dopamine receptor antagonist
SMILES:	CN(C)CCCN1c2ccccc2Sc2ccc(cc12)C(C)=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
44383	BRD-K37814297	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
44579	BRD-K37814297	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
44946	BRD-K37814297	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
45243	BRD-K37814297	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
45815	BRD-K37814297	MCF??7.00	10 uM	6 h	0.27	1.12	0.27	0.0	0.0	0.0
46064	BRD-K37814297	NPC	10 uM	24 h	-0.21	-0.88	0.03	0.23	0.82	0.1
46379	BRD-K37814297	PHH	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
46700	BRD-K37814297	SKB	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
51822	BRD-K37814297	PC3	10 uM	24 h	-0.23	-0.95	0.08	0.0	0.0	0.0

Summary