CMap Candidate Details
Structure:
| CMap ID: | C00662 |
| Pert ID: | BRD-K11717138 |
| Compound Name: | benzbromarone |
| Targets: | ABCC1 |
| MoA: | chloride channel blocker |
| SMILES: | CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 14043 | BRD-K11717138 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.41 | -1.39 | 2.02 |
| 22699 | BRD-K11717138 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 22982 | BRD-K11717138 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 88087 | BRD-K11717138 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 95324 | BRD-K11717138 | A549 | 10 uM | 48 h | -0.22 | -0.92 | 0.06 | -0.31 | -1.06 | 0.73 |
| 95473 | BRD-K11717138 | U2OS | 10 uM | 6 h | -0.19 | -0.81 | 0.0 | -0.29 | -0.96 | 0.44 |
| 121243 | BRD-K11717138 | HA1E | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121299 | BRD-K11717138 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121336 | BRD-K11717138 | PC3 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.24 | 0.87 | 0.17 |
| 121356 | BRD-K11717138 | YAPC | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129269 | BRD-K11717138 | HELA | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129321 | BRD-K11717138 | HT29 | 0.08 uM | 24 h | -0.28 | -1.18 | 0.5 | -0.2 | -0.68 | 0.02 |