CMap Candidate Details
Structure:
| CMap ID: | C00672 |
| Pert ID: | BRD-K91699951 |
| Compound Name: | benzonatate |
| Targets: | SCN5A |
| MoA: | local anesthetic |
| SMILES: | CCCCNc1ccc(cc1)C(=O)OCCOCCOCCOCCOCCOCCOCCOCCOCCOC |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 5237 | BRD-K91699951 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 5373 | BRD-K91699951 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 5696 | BRD-K91699951 | HCC515 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.3 | 1.08 | 0.65 |
| 6301 | BRD-K91699951 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 6601 | BRD-K91699951 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 39369 | BRD-K91699951 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 39824 | BRD-K91699951 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 40114 | BRD-K91699951 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 40375 | BRD-K91699951 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.94 | 0.38 |
| 40533 | BRD-K91699951 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 40922 | BRD-K91699951 | NEU | 10 uM | 24 h | -0.23 | -0.97 | 0.11 | -0.3 | -1.01 | 0.56 |
| 41246 | BRD-K91699951 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |