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CMap Candidate Details

Structure:
CMap ID: C00720
Pert ID: BRD-K92441787
Compound Name: bexarotene
Targets: RXRA|RXRB|RXRG
MoA: retinoid receptor agonist
SMILES: Cc1cc2c(cc1C(=C)c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91112 BRD-K92441787 HUH7 10 uM 72 h -0.37 -1.55 1.43 0.0 0.0 0.0
117019 BRD-K92441787 A375 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117059 BRD-K92441787 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117141 BRD-K92441787 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117186 BRD-K92441787 HEPG2 0.04 uM 24 h -0.18 -0.74 0.0 0.25 0.89 0.2
117271 BRD-K92441787 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117304 BRD-K92441787 PC3 10 uM 24 h 0.0 0.0 0.0 0.38 1.33 1.72
128414 BRD-K92441787 HEK293 1.11 uM 24 h 0.19 0.8 0.0 0.0 0.0 0.0
128523 BRD-K92441787 JURKAT 3.33 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.95
128579 BRD-K92441787 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.37
128617 BRD-K92441787 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128696 BRD-K92441787 THP1 10 uM 24 h -0.27 -1.14 0.42 0.0 0.0 0.0
128750 BRD-K92441787 YAPC 0.04 uM 24 h 0.0 0.0 0.0 -0.31 -1.06 0.73
136204 BRD-K92441787 HA1E 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136247 BRD-K92441787 HELA 2.22 uM 24 h -0.2 -0.83 0.0 0.33 1.18 0.99
136281 BRD-K92441787 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).