CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00742
Pert ID:	BRD-A94543220
Compound Name:	bifonazole
Targets:	CYP2B6
MoA:	sterol demethylase inhibitor
SMILES:	c1cn(cn1)C(c1ccccc1)c1ccc(cc1)-c1ccccc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
25312	BRD-A94543220	VCAP	10 uM	24 h	0.0	0.0	0.0	-0.38	-1.29	1.57
100407	BRD-A94543220	U2OS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
128106	BRD-A94543220	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128133	BRD-A94543220	A549	10 uM	24 h	0.21	0.86	0.01	0.0	0.0	0.0
128164	BRD-A94543220	HEK293	10 uM	24 h	-0.21	-0.88	0.03	0.0	0.0	0.0
128213	BRD-A94543220	MCF10A	0.04 uM	24 h	-0.26	-1.1	0.33	0.0	0.0	0.0
128292	BRD-A94543220	MDAMB231	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
135802	BRD-A94543220	HA1E	0.08 uM	24 h	0.0	0.0	0.0	0.22	0.77	0.06
135887	BRD-A94543220	HELA	2.22 uM	24 h	0.0	0.0	0.0	0.27	0.97	0.35
135935	BRD-A94543220	HT29	2.22 uM	24 h	0.3	1.25	0.54	0.26	0.93	0.28
135976	BRD-A94543220	JURKAT	0.03 uM	24 h	0.0	0.0	0.0	0.32	1.13	0.85
136023	BRD-A94543220	MCF??7.00	2.22 uM	24 h	0.0	0.0	0.0	0.25	0.87	0.17
136053	BRD-A94543220	PC3	2.22 uM	24 h	0.18	0.76	0.0	0.0	0.0	0.0
136083	BRD-A94543220	THP1	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
136122	BRD-A94543220	YAPC	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary