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CMap Candidate Details

Structure:
CMap ID: C00791
Pert ID: BRD-K13566078
Compound Name: BMS-345541
Targets: CHUK|IKBKB
MoA: IKK inhibitor
SMILES: Cc1cnc2c(NCCN)nc3ccc(C)cc3n12
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
71 BRD-K13566078 BJAB 10 uM 4 h 0.0 0.0 0.0 0.0 0.0 0.0
104 BRD-K13566078 HBL1 2.5 uM 24 h -0.26 -1.08 0.28 0.0 0.0 0.0
138 BRD-K13566078 K562 2.5 uM 24 h -0.19 -0.81 0.0 0.33 1.17 0.97
196 BRD-K13566078 KMS34 2.5 uM 24 h -0.25 -1.04 0.21 0.0 0.0 0.0
235 BRD-K13566078 NALM6 2.5 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
275 BRD-K13566078 OCILY10 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
297 BRD-K13566078 OCILY19 2.5 uM 24 h 0.22 0.92 0.04 0.0 0.0 0.0
355 BRD-K13566078 OCILY3 10 uM 4 h 0.0 0.0 0.0 0.0 0.0 0.0
392 BRD-K13566078 SKMEL5 10 uM 24 h -0.18 -0.74 0.0 0.0 0.0 0.0
410 BRD-K13566078 THP1 2.5 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
450 BRD-K13566078 TMD8 0.66 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
33781 BRD-K13566078 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34048 BRD-K13566078 ASC 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.45
34564 BRD-K13566078 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34833 BRD-K13566078 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
36062 BRD-K13566078 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
36208 BRD-K13566078 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36502 BRD-K13566078 SKB 10 uM 24 h -0.18 -0.76 0.0 0.0 0.0 0.0
36780 BRD-K13566078 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91599 BRD-K13566078 HS578T 2.22 uM 6 h 0.0 0.0 0.0 -0.35 -1.17 1.12
91673 BRD-K13566078 MCF??7.00 2.22 uM 6 h 0.0 0.0 0.0 -0.29 -0.98 0.49
91767 BRD-K13566078 SKBR3 2.22 uM 6 h 0.0 0.0 0.0 -0.27 -0.9 0.27
92455 BRD-K13566078 BT20 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92491 BRD-K13566078 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92522 BRD-K13566078 HME1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92622 BRD-K13566078 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92655 BRD-K13566078 LNCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92723 BRD-K13566078 MCF10A 3.33 uM 3 h 0.0 0.0 0.0 -0.22 -0.75 0.07
92786 BRD-K13566078 MDAMB231 0.37 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
95850 BRD-K13566078 NPC 1.11 uM 6 h 0.3 1.23 0.5 0.0 0.0 0.0
95909 BRD-K13566078 YAPC 1.11 uM 6 h 0.0 0.0 0.0 0.2 0.72 0.02
97042 BRD-K13566078 A375 3.33 uM 24 h 0.0 0.0 0.0 0.36 1.27 1.34
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).