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CMap Candidate Details

Structure:
CMap ID: C00081
Pert ID: BRD-A29520968
Compound Name: acifran
Targets: HCAR2|HCAR3
MoA: cholesterol inhibitor
SMILES: CC1(OC(=CC1=O)C(O)=O)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121894 BRD-A29520968 A375 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122008 BRD-A29520968 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122046 BRD-A29520968 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122164 BRD-A29520968 PC3 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130201 BRD-A29520968 A549 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130225 BRD-A29520968 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130256 BRD-A29520968 HEK293 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130287 BRD-A29520968 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130347 BRD-A29520968 JURKAT 0.74 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.37
130396 BRD-A29520968 MCF10A 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130431 BRD-A29520968 MCF??7.00 0.03 uM 24 h -0.21 -0.86 0.01 0.0 0.0 0.0
130448 BRD-A29520968 MDAMB231 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130494 BRD-A29520968 THP1 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130519 BRD-A29520968 YAPC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).