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CMap Candidate Details

Structure:
CMap ID: C00082
Pert ID: BRD-K63736853
Compound Name: acipimox
Targets: HCAR2
MoA: cholesterol inhibitor
SMILES: Cc1cnc(c[n+]1[O-])C(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91308 BRD-K63736853 HUH7 20 uM 72 h 0.0 0.0 0.0 0.29 1.03 0.51
124997 BRD-K63736853 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125025 BRD-K63736853 HELA 10 uM 24 h 0.0 0.0 0.0 0.33 1.17 0.92
125095 BRD-K63736853 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.33 1.16 0.9
125162 BRD-K63736853 THP1 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132979 BRD-K63736853 A375 2.22 uM 24 h -0.23 -0.94 0.08 0.0 0.0 0.0
132996 BRD-K63736853 A549 0.25 uM 24 h -0.25 -1.06 0.26 0.18 0.63 0.0
133048 BRD-K63736853 HEK293 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133116 BRD-K63736853 HT29 0.08 uM 24 h -0.27 -1.14 0.42 0.0 0.0 0.0
133155 BRD-K63736853 JURKAT 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133196 BRD-K63736853 MCF10A 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133260 BRD-K63736853 MDAMB231 0.25 uM 24 h 0.0 0.0 0.0 -0.23 -0.79 0.1
133291 BRD-K63736853 PC3 2.22 uM 24 h 0.0 0.0 0.0 -0.2 -0.68 0.02
133315 BRD-K63736853 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).