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CMap Candidate Details

Structure:
CMap ID: C00085
Pert ID: BRD-K13050541
Compound Name: acivicin
Targets: CTPS1
MoA: gamma glutamyltransferase Inhibitors
SMILES: N[C@H]([C@@H]1CC(Cl)=NO1)C(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122245 BRD-K13050541 A375 4 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122296 BRD-K13050541 HA1E 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122313 BRD-K13050541 HEK293 12 uM 24 h 0.34 1.42 1.06 0.0 0.0 0.0
122328 BRD-K13050541 HELA 1.25 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.15
122356 BRD-K13050541 MCF10A 1.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122385 BRD-K13050541 MCF??7.00 1.25 uM 24 h 0.0 0.0 0.0 -0.39 -1.32 1.71
122411 BRD-K13050541 MDAMB231 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122435 BRD-K13050541 PC3 12 uM 24 h 0.18 0.75 0.0 0.0 0.0 0.0
122467 BRD-K13050541 THP1 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130551 BRD-K13050541 A549 0.3 uM 24 h 0.23 0.94 0.06 0.0 0.0 0.0
130701 BRD-K13050541 HT29 2.5 uM 24 h 0.26 1.08 0.22 -0.27 -0.9 0.29
130830 BRD-K13050541 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).