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CMap Candidate Details

Structure:
CMap ID: C00852
Pert ID: BRD-K84266862
Compound Name: BRL-50481
Targets: PDE7A|PDE7B
MoA: phosphodiesterase inhibitor
SMILES: CN(C)S(=O)(=O)c1cc(ccc1C)[N+]([O-])=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1641 BRD-K84266862 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.74 0.05
1988 BRD-K84266862 HCC515 10 uM 24 h 0.34 1.43 1.11 0.31 1.11 0.72
2641 BRD-K84266862 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39505 BRD-K84266862 A549 10 uM 6 h -0.22 -0.93 0.07 -0.29 -0.98 0.48
39793 BRD-K84266862 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40085 BRD-K84266862 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40349 BRD-K84266862 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40518 BRD-K84266862 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40892 BRD-K84266862 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41213 BRD-K84266862 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41552 BRD-K84266862 SKB 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.47
97019 BRD-K84266862 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97098 BRD-K84266862 PC3 1.11 uM 24 h -0.2 -0.83 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).