CMap Candidate Details
Structure:
| CMap ID: | C00899 |
| Pert ID: | BRD-A01636364 |
| Compound Name: | bupivacaine |
| Targets: | KCNA5|PTGER1|SCN10A|SCN4A |
| MoA: | sodium channel blocker |
| SMILES: | CCCCN1CCCCC1C(=O)Nc1c(C)cccc1C |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 91295 | BRD-A01636364 | HUH7 | 12 uM | 72 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122833 | BRD-A01636364 | A375 | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122846 | BRD-A01636364 | A549 | 10 uM | 24 h | -0.23 | -0.97 | 0.11 | -0.25 | -0.85 | 0.19 |
| 122892 | BRD-A01636364 | HEK293 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 122971 | BRD-A01636364 | HT29 | 1.11 uM | 24 h | 0.22 | 0.91 | 0.04 | -0.37 | -1.24 | 1.29 |
| 123017 | BRD-A01636364 | JURKAT | 0.04 uM | 24 h | 0.21 | 0.89 | 0.02 | 0.0 | 0.0 | 0.0 |
| 123063 | BRD-A01636364 | MCF10A | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.87 | 0.23 |
| 123106 | BRD-A01636364 | MDAMB231 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 123178 | BRD-A01636364 | THP1 | 10 uM | 24 h | -0.23 | -0.97 | 0.11 | 0.0 | 0.0 | 0.0 |
| 131277 | BRD-A01636364 | HA1E | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131303 | BRD-A01636364 | HELA | 0.08 uM | 24 h | 0.26 | 1.09 | 0.23 | 0.3 | 1.06 | 0.61 |
| 131354 | BRD-A01636364 | HUVEC | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.04 | 0.66 |
| 131433 | BRD-A01636364 | MCF??7.00 | 2.22 uM | 24 h | -0.27 | -1.13 | 0.4 | 0.0 | 0.0 | 0.0 |
| 131461 | BRD-A01636364 | PC3 | 0.74 uM | 24 h | 0.25 | 1.06 | 0.18 | -0.24 | -0.79 | 0.11 |
| 131493 | BRD-A01636364 | YAPC | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |