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CMap Candidate Details

Structure:
CMap ID: C00912
Pert ID: BRD-A47706533
Compound Name: buthionine-sulfoximine
Targets: GCLM
MoA: glutathione transferase inhibitor
SMILES: CCCCS(=N)(=O)CC[C@H](N)C(O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
29730 BRD-A47706533 A375 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.85 0.2
30142 BRD-A47706533 A549 10 uM 6 h 0.22 0.94 0.05 0.0 0.0 0.0
30304 BRD-A47706533 ASC 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.06 0.74
30632 BRD-A47706533 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
30915 BRD-A47706533 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31210 BRD-A47706533 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31592 BRD-A47706533 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31807 BRD-A47706533 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32298 BRD-A47706533 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32587 BRD-A47706533 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
33207 BRD-A47706533 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).