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CMap Candidate Details

Structure:
CMap ID: C00950
Pert ID: BRD-K77175907
Compound Name: calcifediol
Targets: VDR
MoA: vitamin D receptor agonist
SMILES: C[C@H](CCCC(C)(C)O)[C@H]1CC[C@@H]2[C@]1(C)CCC\C2=C/C=C1/C[C@@H](O)CCC1=C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33839 BRD-K77175907 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34418 BRD-K77175907 HA1E 10 uM 6 h -0.22 -0.93 0.07 -0.24 -0.82 0.15
34682 BRD-K77175907 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.04 0.66
34957 BRD-K77175907 HEPG2 10 uM 6 h 0.26 1.09 0.24 0.0 0.0 0.0
35199 BRD-K77175907 HT29 10 uM 6 h -0.24 -1.0 0.14 0.0 0.0 0.0
35345 BRD-K77175907 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.83 0.16
35997 BRD-K77175907 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36347 BRD-K77175907 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36644 BRD-K77175907 SKB 10 uM 24 h -0.23 -0.95 0.08 0.0 0.0 0.0
36867 BRD-K77175907 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91118 BRD-K77175907 HUH7 8 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
98827 BRD-K77175907 NPC 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
99087 BRD-K77175907 NEU 10 uM 6 h -0.23 -0.95 0.09 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).