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CMap Candidate Details

Structure:
CMap ID: C00952
Pert ID: BRD-K27316855
Compound Name: calcitriol
Targets: VDR
MoA: vitamin D receptor agonist
SMILES: C[C@H](CCCC(C)(C)O)[C@H]1CC[C@@H]2[C@]1(C)CCC\C2=C/C=C1/C[C@@H](O)C[C@H](O)C1=C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1007 BRD-K27316855 CD34 1.11 uM 6 h 0.0 0.0 0.0 -0.33 -1.09 0.85
1043 BRD-K27316855 HL60 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1171 BRD-K27316855 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1214 BRD-K27316855 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1228 BRD-K27316855 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1356 BRD-K27316855 U2OS 10 uM 48 h -0.26 -1.09 0.33 -0.35 -1.17 1.13
8927 BRD-K27316855 A375 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9394 BRD-K27316855 AGS 1.11 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9705 BRD-K27316855 H1299 1.11 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9928 BRD-K27316855 HA1E 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10178 BRD-K27316855 HCC515 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10489 BRD-K27316855 HCT116 1.11 uM 6 h 0.0 0.0 0.0 -0.29 -0.97 0.46
10763 BRD-K27316855 HEPG2 1.11 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10964 BRD-K27316855 HT29 1.11 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.07
11456 BRD-K27316855 NCIH2073 1.11 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11740 BRD-K27316855 NCIH508 1.11 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12020 BRD-K27316855 NCIH596 1.11 uM 6 h 0.23 0.95 0.06 0.26 0.93 0.26
12767 BRD-K27316855 SW480 1.11 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13247 BRD-K27316855 U937 1.11 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25345 BRD-K27316855 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91140 BRD-K27316855 HUH7 8 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
98747 BRD-K27316855 NPC 10 uM 24 h 0.23 0.97 0.08 0.28 1.0 0.43
99019 BRD-K27316855 NEU 10 uM 6 h 0.0 0.0 0.0 0.23 0.8 0.08
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).