CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00096
Pert ID:	BRD-K33483813
Compound Name:	actarit
Targets:
MoA:	interleukin receptor agonist
SMILES:	CC(=O)Nc1ccc(CC(O)=O)cc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
25359	BRD-K33483813	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
121925	BRD-K33483813	A549	3.33 uM	24 h	0.25	1.04	0.15	0.0	0.0	0.0
121991	BRD-K33483813	HELA	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
122072	BRD-K33483813	HUVEC	3.33 uM	24 h	0.0	0.0	0.0	-0.24	-0.81	0.14
122121	BRD-K33483813	MCF??7.00	0.125 uM	24 h	0.0	0.0	0.0	-0.22	-0.74	0.05
130189	BRD-K33483813	A375	0.25 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
130243	BRD-K33483813	HA1E	0.74 uM	24 h	-0.23	-0.94	0.08	0.0	0.0	0.0
130268	BRD-K33483813	HEK293	0.08 uM	24 h	-0.27	-1.13	0.41	-0.29	-0.96	0.44
130329	BRD-K33483813	HT29	0.74 uM	24 h	0.25	1.06	0.18	-0.2	-0.67	0.01
130373	BRD-K33483813	JURKAT	0.01 uM	24 h	0.19	0.8	0.0	-0.23	-0.78	0.09
130416	BRD-K33483813	MCF10A	0.74 uM	24 h	0.0	0.0	0.0	-0.23	-0.79	0.11
130463	BRD-K33483813	MDAMB231	0.25 uM	24 h	0.24	0.99	0.1	0.0	0.0	0.0
130484	BRD-K33483813	PC3	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
130505	BRD-K33483813	THP1	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
130539	BRD-K33483813	YAPC	0.25 uM	24 h	0.28	1.17	0.36	-0.37	-1.24	1.34

Summary