CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00965
Pert ID:	BRD-K84091759
Compound Name:	candesartan
Targets:	AGTR1
MoA:	angiotensin receptor antagonist
SMILES:	CCOc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
52203	BRD-K84091759	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
91138	BRD-K84091759	HUH7	8 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
95313	BRD-K84091759	A549	10 uM	48 h	0.0	0.0	0.0	-0.31	-1.05	0.7
95455	BRD-K84091759	U2OS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
126009	BRD-K84091759	HA1E	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
126088	BRD-K84091759	HUVEC	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
126135	BRD-K84091759	JURKAT	10 uM	24 h	0.0	0.0	0.0	-0.22	-0.75	0.07
126188	BRD-K84091759	MCF10A	0.125 uM	24 h	0.0	0.0	0.0	0.32	1.15	0.88
126268	BRD-K84091759	PC3	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
126306	BRD-K84091759	THP1	0.04 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
126344	BRD-K84091759	YAPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134012	BRD-K84091759	A375	0.03 uM	24 h	0.21	0.86	0.01	0.27	0.94	0.3
134110	BRD-K84091759	HEK293	0.74 uM	24 h	0.0	0.0	0.0	-0.33	-1.11	0.9
134155	BRD-K84091759	HELA	0.01 uM	24 h	0.2	0.85	0.01	0.0	0.0	0.0
134185	BRD-K84091759	HT29	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
134263	BRD-K84091759	MDAMB231	0.01 uM	24 h	0.0	0.0	0.0	0.32	1.13	0.85

Summary