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CMap Candidate Details

Structure:
CMap ID: C00972
Pert ID: BRD-K61192372
Compound Name: capecitabine
Targets: TYMS
MoA: DNA synthesis inhibitor; thymidylate synthase inhibitor
SMILES: CCCCCOC(=O)Nc1nc(=O)n(cc1F)[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
29900 BRD-K61192372 A375 10 uM 6 h 0.22 0.91 0.03 0.0 0.0 0.0
30086 BRD-K61192372 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
30498 BRD-K61192372 ASC 10 uM 24 h 0.0 0.0 0.0 0.33 1.16 0.9
30797 BRD-K61192372 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31090 BRD-K61192372 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31398 BRD-K61192372 HEPG2 10 uM 6 h -0.27 -1.12 0.39 0.0 0.0 0.0
31538 BRD-K61192372 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
32053 BRD-K61192372 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.89 0.27
32477 BRD-K61192372 NPC 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.7 0.03
32659 BRD-K61192372 PC3 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.9
33080 BRD-K61192372 SKB 10 uM 24 h -0.16 -0.67 0.0 0.3 1.07 0.63
33322 BRD-K61192372 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).