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CMap Candidate Details

Structure:
CMap ID: C00976
Pert ID: BRD-K50590187
Compound Name: capsaicin
Targets: CFTR|TRPV1
MoA: TRPV agonist
SMILES: COc1cc(CNC(=O)CCCC\C=C\C(C)C)ccc1O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8948 BRD-K50590187 A375 150 uM 24 h -0.23 -0.94 0.08 0.0 0.0 0.0
9208 BRD-K50590187 A549 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9435 BRD-K50590187 AGS 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9738 BRD-K50590187 H1299 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9888 BRD-K50590187 HA1E 150 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10134 BRD-K50590187 HCC515 150 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10528 BRD-K50590187 HCT116 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10795 BRD-K50590187 HEPG2 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11280 BRD-K50590187 MCF??7.00 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11500 BRD-K50590187 NCIH2073 150 uM 6 h 0.0 0.0 0.0 -0.37 -1.25 1.35
12062 BRD-K50590187 NCIH596 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12327 BRD-K50590187 NOMO1 150 uM 6 h 0.0 0.0 0.0 -0.28 -0.94 0.39
12450 BRD-K50590187 PC3 150 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12803 BRD-K50590187 SW480 150 uM 6 h 0.0 0.0 0.0 0.34 1.19 1.03
13629 BRD-K50590187 VCAP 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91147 BRD-K50590187 HUH7 10 uM 72 h 0.0 0.0 0.0 -0.26 -0.86 0.22
98759 BRD-K50590187 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98905 BRD-K50590187 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125341 BRD-K50590187 HEK293 0.04 uM 24 h 0.0 0.0 0.0 0.26 0.91 0.23
125362 BRD-K50590187 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125410 BRD-K50590187 JURKAT 10 uM 24 h 0.2 0.82 0.0 0.0 0.0 0.0
125534 BRD-K50590187 THP1 10 uM 24 h -0.22 -0.93 0.07 0.33 1.17 0.93
133470 BRD-K50590187 HT29 0.74 uM 24 h -0.24 -0.99 0.14 -0.25 -0.85 0.19
133533 BRD-K50590187 MCF10A 0.01 uM 24 h -0.23 -0.98 0.11 0.22 0.8 0.08
133574 BRD-K50590187 MDAMB231 0.25 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.58
133652 BRD-K50590187 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).