Investigational Drug Details
| Drug ID: | D424 |
| Drug Name: | Arachidonic Acid |
| Synonyms: | |
| Type: | small molecule |
| DrugBank ID: | DB04557 |
| DrugBank Description: | An unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. [PubChem] |
| PubChem ID: | 444899 |
| CasNo: | 506-32-1 |
| Repositioning for NAFLD: | Yes |
| SMILES: | CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O |
| Structure: |
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| InChiKey: | YZXBAPSDXZZRGB-DOFZRALJSA-N |
| Molecular Weight: | 304.4669 |
| DrugBank Targets: | Peroxisome proliferator-activated receptor alpha; Bile acid receptor; Retinoic acid receptor RXR-alpha; Prostaglandin G/H synthase 1; 14 kDa fatty acid-binding protein |
| DrugBank MoA: | |
| DrugBank Pharmacology: | |
| DrugBank Indication: | |
| Targets: | |
| Therapeutic Category: | |
| Clinical Trial Progress: | |
| Latest Progress: |
| Trial ID | Source ID | Phases | Status | Study Results | Start Date | Last Update Posted | |
|---|---|---|---|---|---|---|---|
| L0521 | NCT01663103 | PHASE4 | COMPLETED | YES | 2012-08 | 2016-09-12 | Details |
| L3855 | NCT01499095 | PHASE3 | COMPLETED | YES | 2011-12 | 2022-03-23 | Details |
| L4560 | NCT02481141 | COMPLETED | YES | 2014-07 | 2018-05-22 | Details | |
| L4784 | NCT01508923 | PHASE2 | COMPLETED | NO | 2001-05 | 2017-01-24 | Details |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
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| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
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