Investigational Drug Details
| Drug ID: | D468 |
| Drug Name: | Parecoxib |
| Synonyms: | |
| Type: | small molecule |
| DrugBank ID: | DB08439 |
| DrugBank Description: | Parecoxib is a water-soluble and injectable prodrug of valdecoxib. It is marketed as Dynastat in the European Union. Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx). As it is injectable, it can be used perioperatively when patients are unable to take oral medications. It is approved through much of Europe for short term perioperative pain control much in the same way ketorolac (Toradol) is used in the United States. A letter of non-approval for parecoxib was issued by the FDA in 2005. |
| PubChem ID: | 119828 |
| CasNo: | 198470-84-7 |
| Repositioning for NAFLD: | Yes |
| SMILES: | CCC(=O)NS(=O)(=O)C1=CC=C(C=C1)C1=C(C)ON=C1C1=CC=CC=C1 |
| Structure: |
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| InChiKey: | TZRHLKRLEZJVIJ-UHFFFAOYSA-N |
| Molecular Weight: | 370.422 |
| DrugBank Targets: | Prostaglandin G/H synthase 2; Lactotransferrin |
| DrugBank MoA: | |
| DrugBank Pharmacology: | |
| DrugBank Indication: | Used for short term perioperative pain control. |
| Targets: | |
| Therapeutic Category: | |
| Clinical Trial Progress: | |
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