Investigational Drug Details
| Drug ID: | D426 |
| Drug Name: | Methaqualone |
| Synonyms: | |
| Type: | small molecule |
| DrugBank ID: | DB04833 |
| DrugBank Description: | Methaqualone is a sedative-hypnotic drug that is similar in effect to barbiturates, a general central nervous system depressant. The sedative-hypnotic activity was first noted by Indian researchers in the 1950s and in 1962 methaqualone itself was patented in the US by Wallace and Tiernan. Its use peaked in the early 1970s as a hypnotic, sedative, and muscle relaxant commonly used for insomnia. It has also been used illegally as a recreational drug, commonly known as Quaaludes, Sopors, Ludes or Mandrax (particularly in the 1970s in North America) depending on the manufacturer. Since at least 2001, it has been widely used in South Africa, where it is commonly referred to as "smarties" or "geluk-tablette" (meaning happy tablets). Clandestinely produced methaqualone is still seized by government agencies and police forces around the world. |
| PubChem ID: | 6292 |
| CasNo: | 72-44-6 |
| Repositioning for NAFLD: | Yes |
| SMILES: | CC1=CC=CC=C1N1C(C)=NC2=CC=CC=C2C1=O |
| Structure: |
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| InChiKey: | JEYCTXHKTXCGPB-UHFFFAOYSA-N |
| Molecular Weight: | 250.2952 |
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| DrugBank Indication: | For the treatment of insomnia, and as a sedative and muscle relaxant. |
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