Investigational Drug Details
| Drug ID: | D541 |
| Drug Name: | Cortisone |
| Synonyms: | |
| Type: | small molecule |
| DrugBank ID: | DB14681 |
| DrugBank Description: | A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to the active metabolite hydrocortisone. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726) |
| PubChem ID: | 222786 |
| CasNo: | 53-06-5 |
| Repositioning for NAFLD: | Yes |
| SMILES: | [H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)CC(=O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C |
| Structure: |
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| InChiKey: | MFYSYFVPBJMHGN-ZPOLXVRWSA-N |
| Molecular Weight: | 360.444 |
| DrugBank Targets: | |
| DrugBank MoA: | |
| DrugBank Pharmacology: | |
| DrugBank Indication: | |
| Targets: | |
| Therapeutic Category: | |
| Clinical Trial Progress: | |
| Latest Progress: |
| Trial ID | Source ID | Phases | Status | Study Results | Start Date | Last Update Posted | |
|---|---|---|---|---|---|---|---|
| L3223 | NCT01375322 | PHASE4 | COMPLETED | NO | 2007-06 | 2011-06-17 | Details |
| L4892 | NCT06192108 | PHASE3 | ACTIVE_NOT_RECRUITING | NO | 2024-01-10 | 2025-02-28 | Details |
| L6722 | NCT02752828 | PHASE3 | COMPLETED | NO | 2016-05-23 | 2020-06-16 | Details |
| L7178 | NCT00982254 | PHASE1 | COMPLETED | NO | 2001-10 | 2009-09-23 | Details |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
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| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
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