In vitro & In vivo Models
In vitro & in vivo models of CKD are manually extracted from research articles.
157 records.
| Model ID | Category | Class | Type | Model | Description | Source | Reference (PMIDs) |
|---|---|---|---|---|---|---|---|
| M021 | In vitro | Tissue model | Brain | Brain | Inhibition of specific [3H]clonidine binding (0.4 nM) to rat brain membranes Alpha-2 adrenergic receptor | Oryctolagus cuniculus | 6142954 |
| M022 | In vitro | Cell line | Cell line | C-33-A | C-33-A | Homo sapiens | 18249537 |
| M023 | In vitro | Cell line | Cell line | C2C12 | C2C12 (Myoblast cells) | Mus musculus | |
| M024 | In vitro | Cell line | Cell line | C33a | Inhibition of Akt2 phosphorylation in human C33a cells | Homo sapiens | 18294842 |
| M025 | In vitro | Cell line | Cell line | C6 | C6 (Glioma cells) | Rattus norvegicus | 20809632 |
| M026 | In vitro | Cell line | Cell line | CHO | CHO (Ovarian cells) | Cricetulus griseus | 7562902 |
| M027 | In vitro | Cell line | Cell line | CHO-C10 | Effective concentration at Alpha-2A adrenergic receptor from CHO-C10 cells | Unknown | 9016324 |
| M028 | In vitro | Cell line | Cell line | CHO-K1 | CHO-K1 (Ovarian cells) | Cricetulus griseus | 11738577 |
| M029 | In vitro | Cell line | Cell line | CHOT | Inhibition of human INSR phosphorylation over expressed in CHOT cells after 60 mins by immunoblotting | Homo sapiens | 22612866 |
| M030 | In vitro | Cell line | Tumor-derived cell line | COLO 205 | COLO 205 (Colon adenocarcinoma cells) | Homo sapiens | |
| M031 | In vitro | Cell line | Cell line | COS | In vitro transcriptional activation in COS cells expressing human peroxisome proliferator activated receptor gamma PPAR-GAL4 chimera; Not determined | Homo sapiens | 12729668 |
| M032 | In vitro | Cell line | Cell line | COS-1 | COS-1 (Kidney cells) | Chlorocebus aethiops | 12617924 |
| M033 | In vitro | Cell line | Cell line | COS-7 | COS-7 (Kidney cells) | Chlorocebus aethiops | 15664804 |
| M034 | In vitro | Cell line | Cell line | COS7 | Partial agonist activity at full length human PPARG expressed in African green monkey COS7 cells assessed as increase in receptor activation at 10 uM incubated for 24 hrs by luciferase reporter assay | Homo sapiens | 32272420 |
| M035 | In vitro | Cell line | Cell line | CV-1 | CV-1 (Kidney cells) | Chlorocebus aethiops | 9836620 |
| M036 | In vitro | Cell line | Cell line | Caco- 2/TC7 | Transactivation potency was measured by luciferase activity in Caco- 2/TC7 cells transiently co-transfected for the fusion-protein Gal4-PPAR gamma | Unknown | 12443777 |
| M037 | In vitro | Cell line | Tumor-derived cell line | Caco-2 | Caco-2 (Colon adenocarcinoma cells) | Homo sapiens | 18222570 |
| M038 | In vitro | Cell line | Cell line | Chem-1 | Displacement of [125I]-glucagon from human glucagon receptor expressed in Chem-1 cell membranes after 6 to 10 hrs by scintillation proximity assay | Homo sapiens | 26271588 |
| M039 | In vitro | Cell line | Cell line | Cos1 | Agonist activity at PPARgamma expressed in human Cos1 cells after 18 hrs by SEAP reporter gene assay | Homo sapiens | 24900488 |
| M040 | In vitro | Cell line | Cell line | DOHH-2 | DOHH-2 | Homo sapiens | 35051576 |