In vitro & In vivo Models
In vitro & in vivo models of CKD are manually extracted from research articles.
157 records.
| Model ID | Category | Class | Type | Model | Description | Source | Reference (PMIDs) |
|---|---|---|---|---|---|---|---|
| M061 | In vitro | Cell line | Cell line | HMEC | HMEC (Microvascular endothelial cells) | Homo sapiens | |
| M062 | In vitro | Cell line | Tumor-derived cell line | HN5 | HN5 (Squamous cell carcinoma) | Homo sapiens | |
| M063 | In vitro | Cell line | Tumor-derived cell line | HT-29 | HT-29 (Colon adenocarcinoma cells) | Homo sapiens | 16392816 |
| M064 | In vitro | Cell line | Cell line | HTB-85 | Inhibition of NPP1 in human HTB-85 cells assessed as production of p-nitrophenol using pnp-TMP at 100 uM measured after 20 mins by spectrophotometry | Homo sapiens | 24083941 |
| M065 | In vitro | Cell line | Cell line | HTLA | HEK293 cell line stably expressing a tTA-dependent luciferase reporter and a beta-arrestin2-TEV fusion gene | Homo sapiens | 35195401 |
| M066 | In vitro | Cell line | Cell line | HUVEC | HUVEC (Umbilical vein endothelial cells) | Homo sapiens | |
| M067 | In vitro | Cell line | Tumor-derived cell line | HeLa | HeLa (Cervical adenocarcinoma cells) | Homo sapiens | 19275963 |
| M068 | In vitro | Cell line | Cell line | HepG2 | HepG2 (Hepatoblastoma cells) | Homo sapiens | 10714503 |
| M069 | In vitro | Cell line | Cell line | HepG2/C3A | Activation of human PPARgamma ligand binding domain-mediated transcriptional activity in human HepG2/C3A cells co-transfected with fused Gal4-LBD by cotransfection assay relative to rosiglitazone | Homo sapiens | 17403688 |
| M070 | In vitro | Cell line | Cell line | HepG3/C3A | Activation of HNFalpha transcriptional activity in human HepG3/C3A cells transfected with ApoB-luc assessed as activation of luciferase reporter gene after 24 hrs | Homo sapiens | 19729315 |
| M071 | In vitro | Cell line | Cell line | HepaR | Agonist activity at PPARgamma in human HepaR cells assessed as increase in HMGCS2 gene expression at 1 uM incubated for 1 day by quantitative PCR method relative to untreated control | Homo sapiens | 25497132 |
| M072 | In vitro | Cell line | Cell line | Hepatocyte | Hepatocytes | Homo sapiens | 25001129 |
| M073 | In vitro | Cell line | Cell line | HuNS1 | HuNS1 | Homo sapiens | |
| M074 | In vitro | Cell line | Tumor-derived cell line | Huh-7 | Huh-7 (Hepatocellular carcinoma) | Homo sapiens | 16366601 |
| M075 | In vitro | Cell line | Cell line | JEG-3 | JEG-3 | Homo sapiens | 9873454 |
| M076 | In vitro | Cell line | Cell line | JIMT-1 | JIMT-1 | Homo sapiens | 36584630 |
| M077 | In vitro | Cell line | Cell line | JJN-3 | JJN-3 | Homo sapiens | 28837922 |
| M078 | In vitro | Cell line | Cell line | JeKo-1 | JeKo-1 | Homo sapiens | 36399923 |
| M079 | In vitro | Cell line | Cell line | Jurkat | Jurkat (Acute leukemic T-cells) | Homo sapiens | 25372368 |
| M080 | In vitro | Cell line | Cell line | K-562, COLO 205, SK-N-BE(2) and MV-4-11 | Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry. | Homo sapiens | 29191878 |