In vitro & In vivo Models
In vitro & in vivo models of CKD are manually extracted from research articles.
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PPAR17 records.
| Model ID | Category | Class | Type | Model | Description | Source | Reference (PMIDs) |
|---|---|---|---|---|---|---|---|
| M001 | In vitro | Cell line | Cell line | 293F | Inhibition of recombinant human preprorenin expressed in human 293F cells using angiotensinogen as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins by ELISA | Homo sapiens | 27774132 |
| M002 | In vitro | Cell line | Cell line | 293H-DA | Agonist activity at PPARgamma LBD in human 293H DA cells after 16 hrs by TR-FRET activation reporter assay | Homo sapiens | 22582973 |
| M009 | In vitro | Cell line | Cell line | A673 | A673 | Homo sapiens | |
| M011 | In vitro | Cell line | Cell line | Ac2F | Agonist activity at full length human PPARgamma transfected in rat Ac2F cells cotransfected with PPRE-TK-luc assessed as induction of transactivation activity at 10 ug/ml by luciferase reporter gene assay relative to control | Homo sapiens | 23189988 |
| M016 | In vitro | Cell line | Cell line | BL21 | Inhibitory concentration against human PTP1B expressed in Escherichia coli BL21 cells | Homo sapiens | 16039123 |
| M029 | In vitro | Cell line | Cell line | CHOT | Inhibition of human INSR phosphorylation over expressed in CHOT cells after 60 mins by immunoblotting | Homo sapiens | 22612866 |
| M032 | In vitro | Cell line | Cell line | COS-1 | COS-1 (Kidney cells) | Chlorocebus aethiops | 12617924 |
| M034 | In vitro | Cell line | Cell line | COS7 | Partial agonist activity at full length human PPARG expressed in African green monkey COS7 cells assessed as increase in receptor activation at 10 uM incubated for 24 hrs by luciferase reporter assay | Homo sapiens | 32272420 |
| M037 | In vitro | Cell line | Tumor-derived cell line | Caco-2 | Caco-2 (Colon adenocarcinoma cells) | Homo sapiens | 18222570 |
| M041 | In vitro | Cell line | Cell line | EJM | EJM | Homo sapiens | |
| M042 | In vitro | Tissue model | Epididymis | Epididymis | Concentration that causes 50% inhibition of mammalian alpha-mannosidase was determined in rat epididymis | Rattus norvegicus | 7966130 |
| M048 | In vitro | Cell line | Cell line | HEK | Displacement of 2-[125I]iodoMLT from human MT2 receptor stably expressed in HEK cells incubated for 120 mins | Homo sapiens | 36150258 |
| M049 | In vitro | Cell line | Cell line | HEK-293T | HEK-293T (A derivative of HEK-293 cells containing the SV40 T-antigen) | Homo sapiens | 11472221 |
| M051 | In vitro | Cell line | Cell line | HEK293-A | HEK293-A | Homo sapiens | 23137448 |
| M061 | In vitro | Cell line | Cell line | HMEC | HMEC (Microvascular endothelial cells) | Homo sapiens | |
| M063 | In vitro | Cell line | Tumor-derived cell line | HT-29 | HT-29 (Colon adenocarcinoma cells) | Homo sapiens | 16392816 |
| M113 | In vitro | Cell line | Cell line | NCI-H929 | NCI-H929 | Homo sapiens |