Therapeutic Strategy Details
| Strategy ID: | S12 |
| Strategy: | enhance lipid metabolism |
| Other Terms: | Enhance lipid metabolism; Improve insulin resistance; Anti-oxidative stress; Anti-fibrosis; Enhance lipid metabolism; Enhance lipid metabolism; Anti-inflammatory; Anti-fibrosis; Enhance lipid metabolism; Enhance lipid metabolism; Anti-inflammatory; Anti-inflammatory; Improve insulin resistance; Enhance lipid metabolism; Regulating intestinal flora; Anti-hypertensive; Improve insulin resistance; Enhance lipid metabolism; Anti-inflammatory; Improve insulin resistance; Enhance lipid metabolism; Regulating intestinal flora; Anti-fibrosis; Anti-platelet aggregation; Enhance lipid metabolism; Enhance lipid metabolism; Anti-lipogenesis; Anti-fibrosis; Enhance lipid metabolism; Improve insulin resistance; Anti-inflammatory; Anti-fibrosis; Enhance lipid metabolism; Regulating intestinal flora; Improve insulin resistance; Enhance lipid metabolism; Anti-inflammatory; Enhance lipid metabolism; Anti-oxidative stress; Anti-inflammatory; Anti-hypertensive; Enhance lipid metabolism; Anti-apoptosis; Enhance lipid metabolism; Anti-hypertensive; Enhance lipid metabolism; Anti-platelet aggregation; Enhance lipid metabolism; Anti-platelet aggregation; Enhance lipid metabolism; Anti-inflammatory; Anti-fibrosis; Anti-oxidative stress |
| Related Targets: | PPAR; FXR; AMPK; PPAR; Smad2/3; Smad4; PCSK9; AMPK; ACE; SGLT2; HIF; SIRT1 |
| Related Drugs: | Berberine; miR-9-5p; obeticholic acid (OCA; 6-ethyl chenodeoxycholic acid); tropifexor; nidufexor; Pemafibrate; conventional fibrates; Tripterygium wilfordii Hook F; berberine; Tectorigenin; Rehmannia glutinosa leaves total glycoside; evolocumab; statin products; icodextrin dialysate; insulin; dual antiplatelet therapy; statins; beta-blockers; Liraglutide; ACE inhibitors; ATsub1/sub receptor antagonists; N-acetyl-seryl-aspartyl-lysyl-proline; glycolysis inhibitors; prolyl oligopeptidase inhibitor S17092; imidapril; TA-606; dapagliflozin; streptozocin; fenofibrate; inulin; Sodium-glucose cotransporter 2 inhibitors; captopril; enalaprilate; lisinopril; losartan; valsartan; furosemide; pravastatin; simvastatin; fenofibrate; miRNA antagomiR; captopril; tiopronin; active form of dalcetrapib; active metabolite of prasugrel, R-138727; statins; topiroxostat; siXDH |
| Mechanism: | |
| Reference (PMIDs): | 31734944; 31914684; 31940200; 31950425; 31953719; 32005442; 32014572; 32028239; 32046605; 32063216; 32162781; 32247822; 32352559; 32444604; 32446306; 32526852; 32534886; 32545617; 32628541; 32744915; 32969145; 33050202 |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
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| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress |
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| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria |
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| Article ID | PMID | Source | Title |
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