Therapeutic Strategy Details
| Strategy ID: | S01 |
| Strategy: | anti-apoptosis |
| Other Terms: | Anti-inflammatory; Anti-apoptosis; Anti-oxidative stress; Anti-inflammatory; Anti-apoptosis; Anti-apoptosis; Anti-apoptosis; Anti-oxidative stress; Anti-inflammatory; inducing apoptosis in those cells; Anti-fibrosis; Anti-inflammatory; Anti-apoptosis; Anti-inflammatory; Anti-oxidative stress; Anti-apoptosis; Anti-apoptosis; Enhance lipid metabolism; Anti-oxidative stress; Anti-fibrosis; Anti-apoptosis; Anti-inflammatory; Anti-fibrosis; Anti-apoptosis; Anti-oxidative stress; Anti-inflammatory; Anti-fibrosis; Anti-apoptosis; Anti-oxidative stress; Anti-apoptosis; Anti-fibrosis; Anti-apoptosis |
| Related Targets: | MAPK; caspase-3; Bcl-2; TNF-α; IL-1β; IL-6; podocin; nephrin; IL-1β; IL-6; TNF-α; HO-1; NF-κB; VDR; p38 MAPK; NF-κB; PPAR; AMPK; AMPK; NOX4; caspase-3; NOX4; ERK; Bcl-2; Nrf2; p53; Smad2/3; NOX4 |
| Related Drugs: | streptozotocin; Oleuropein; NS-398; iN/i-acetylcysteine; aminoguanidine; metformin; l-cysteine; Astragalus; Salvia miltrorrhiza; Polygala fallax Hemsl; compound Sanqi granules; metformin; Okadaic acid; miR-218 inhibitor; Gushen Jiedu capsule; Hirudin; Akebia saponin D; STZ; calcitriol; streptozocin; 1,25-dihydroxyvitamin D3; anisomycin; Echinacoside; PDTC; fenofibrate; miRNA antagomiR; dencichine; canagliflozin; isoprenaline; streptozotocin; recombinant human clusterin protein; Chloroquine; Amodiaquine; Streptozotocin; angiotensin II; calycosin; mitoquinone; ML385; Calcium dobesilate; FK506; SIS3; Forskolin; recombinant thrombomodulin |
| Mechanism: | |
| Reference (PMIDs): | 31549412; 31755322; 31820187; 31963523; 32000547; 32004509; 32028854; 32029775; 32066115; 32344355; 32432759; 32556611; 32626964; 32628541; 32721462; 32798559; 32887916; 32913257; 32924342; 32974919; 32999213; 33011276; 33011612; 33019979; 33046439; 33069430 |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
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| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress |
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| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria |
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| Article ID | PMID | Source | Title |
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