Therapeutic Target Details
| Target ID: | T15 |
| Target Name: | Steryl-sulfatase |
| Synonyms: | ARSC1; Steryl-sulfatase; Arylsulfatase C; Estrone sulfatase; Steroid sulfatase; Steryl-sulfate sulfohydrolase; ASC; 3.1.6.2 |
| GENE: | STS |
| Action: | INHIBITOR |
| Class: | Hydrolase |
| UniProtKB ID: | P08842 |
| Entry Name: | STS_HUMAN |
| Related Drugs: | Irosustat |
| Mechanism: | Steryl-sulfatase inhibitor |
| Reference (PMIDs): | 10910045 |
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress |
|---|
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria |
|---|
| Compound ID | Source ID | Source Type | Compound Name | Molecular Weight | Molecular Formula | Molecular Species | |
|---|---|---|---|---|---|---|---|
| B008663 | CHEMBL11548 | Small molecule | 227.24 | C9H9NO4S | NEUTRAL | Details | |
| B008684 | CHEMBL11382 | Small molecule | 241.22 | C9H7NO5S | NEUTRAL | Details | |
| B008693 | CHEMBL269221 | Small molecule | 255.25 | C10H9NO5S | NEUTRAL | Details | |
| B008694 | CHEMBL11185 | Small molecule | 255.25 | C10H9NO5S | NEUTRAL | Details | |
| B008747 | CHEMBL275331 | Small molecule | 269.28 | C11H11NO5S | NEUTRAL | Details | |
| B027626 | CHEMBL135 | Small molecule | ESTRADIOL | 272.39 | C18H24O2 | NEUTRAL | Details |
| B030743 | CHEMBL23067 | Small molecule | 228.48 | C2H4Cl3NO3S | NEUTRAL | Details | |
| B030767 | CHEMBL23864 | Small molecule | 191.18 | C6H6FNO3S | NEUTRAL | Details | |
| B030768 | CHEMBL23865 | Small molecule | 191.18 | C6H6FNO3S | NEUTRAL | Details | |
| B030788 | CHEMBL23305 | Small molecule | 252.09 | C6H6BrNO3S | NEUTRAL | Details |
| Article ID | PMID | Source | Title |
|---|