Therapeutic Target Details
| Target ID: | T17 |
| Target Name: | Protein-tyrosine phosphatase 1B |
| Synonyms: | PTP1B; Tyrosine-protein phosphatase non-receptor type 1; Protein-tyrosine phosphatase 1B; PTP-1B; 3.1.3.48 |
| GENE: | PTPN1 |
| Action: | |
| Class: | Target is a single protein chain |
| UniProtKB ID: | P18031 |
| Entry Name: | PTPN1_HUMAN |
| Related Drugs: | |
| Mechanism: | |
| Reference (PMIDs): |
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress |
|---|
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria |
|---|
| Compound ID | Source ID | Source Type | Compound Name | Molecular Weight | Molecular Formula | Molecular Species | |
|---|---|---|---|---|---|---|---|
| B000666 | CHEMBL408 | Small molecule | TROGLITAZONE | 441.55 | C24H27NO5S | NEUTRAL | Details |
| B000993 | CHEMBL265622 | Small molecule | 503.5 | C24H20F3N3O4S | ACID | Details | |
| B001129 | CHEMBL6637 | Small molecule | 501.46 | C25H22F3N3O5 | ACID | Details | |
| B001162 | CHEMBL267877 | Small molecule | 567.5 | C29H21F4N3O5 | ACID | Details | |
| B001174 | CHEMBL6518 | Small molecule | 643.66 | C33H36F3N3O7 | ACID | Details | |
| B001175 | CHEMBL203751 | Small molecule | 607.54 | C31H24F3N3O7 | ACID | Details | |
| B001177 | CHEMBL6845 | Small molecule | 339.35 | C18H17N3O4 | ACID | Details | |
| B001178 | CHEMBL267740 | Small molecule | 418.49 | C25H26N2O4 | ACID | Details | |
| B001180 | CHEMBL265665 | Small molecule | 643.66 | C33H36F3N3O7 | ACID | Details | |
| B001224 | CHEMBL7314 | Small molecule | 507.37 | C24H24Cl2N2O6 | ACID | Details |
| Article ID | PMID | Source | Title |
|---|