Therapeutic Target Details
| Target ID: | T20 |
| Target Name: | Hepatocyte nuclear factor 4-alpha |
| Synonyms: | HNF4; NR2A1; TCF14; Hepatocyte nuclear factor 4-alpha; Nuclear receptor subfamily 2 group A member 1; Transcription factor 14; Transcription factor HNF-4; HNF-4-alpha; TCF-14 |
| GENE: | HNF4A |
| Action: | ACTIVATOR |
| Class: | Target is a single protein chain |
| UniProtKB ID: | P41235 |
| Entry Name: | HNF4A_HUMAN |
| Related Drugs: | Alverine |
| Mechanism: | Hepatocyte nuclear factor 4-alpha activator |
| Reference (PMIDs): | 11697552; 17934514; 20003095; 23488786; 23675775; 24147869; 25199966 |
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress |
|---|
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria |
|---|
| Compound ID | Source ID | Source Type | Compound Name | Molecular Weight | Molecular Formula | Molecular Species | |
|---|---|---|---|---|---|---|---|
| B001598 | CHEMBL7135 | Small molecule | 257.24 | C14H11NO4 | NEUTRAL | Details | |
| B001809 | CHEMBL7174 | Small molecule | 213.19 | C12H7NO3 | NEUTRAL | Details | |
| B001860 | CHEMBL6980 | Small molecule | 227.22 | C13H9NO3 | NEUTRAL | Details | |
| B001878 | CHEMBL7644 | Small molecule | 243.22 | C13H9NO4 | NEUTRAL | Details | |
| B001917 | CHEMBL269488 | Small molecule | 243.22 | C13H9NO4 | NEUTRAL | Details | |
| B001998 | CHEMBL7645 | Small molecule | 243.22 | C13H9NO4 | NEUTRAL | Details | |
| B002036 | CHEMBL7258 | Small molecule | 229.19 | C12H7NO4 | NEUTRAL | Details | |
| B593303 | CHEMBL611816 | Small molecule | 211.22 | C13H9NO2 | NEUTRAL | Details | |
| B2040616 | CHEMBL3719031 | Small molecule | 323.39 | C20H21NO3 | NEUTRAL | Details | |
| B2040617 | CHEMBL3718791 | Small molecule | 323.39 | C20H21NO3 | ACID | Details |
| Article ID | PMID | Source | Title |
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