Therapeutic Target Details
| Target ID: | T21 |
| Target Name: | Uncharacterized aarF domain-containing protein kinase 4 |
| Synonyms: | Synonyms=ADCK4; Atypical kinase COQ8B, mitochondrial; AarF domain-containing protein kinase 4; Coenzyme Q protein 8B; 2.7.-.- |
| GENE: | COQ8B |
| Action: | |
| Class: | Target is a single protein chain |
| UniProtKB ID: | Q96D53 |
| Entry Name: | COQ8B_HUMAN |
| Related Drugs: | |
| Mechanism: | |
| Reference (PMIDs): |
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress |
|---|
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria |
|---|
| Compound ID | Source ID | Source Type | Compound Name | Molecular Weight | Molecular Formula | Molecular Species | |
|---|---|---|---|---|---|---|---|
| B000250 | CHEMBL10 | Small molecule | SB-203580 | 377.44 | C21H16FN3OS | NEUTRAL | Details |
| B000273 | CHEMBL440084 | Small molecule | SB-431542 | 384.4 | C22H16N4O3 | NEUTRAL | Details |
| B013048 | CHEMBL535 | Small molecule | SUNITINIB | 398.48 | C22H27FN4O2 | BASE | Details |
| B014221 | CHEMBL14762 | Small molecule | SELICICLIB | 354.46 | C19H26N6O | NEUTRAL | Details |
| B014366 | CHEMBL428690 | Small molecule | ALVOCIDIB | 401.85 | C21H20ClNO5 | NEUTRAL | Details |
| B014785 | CHEMBL553 | Small molecule | ERLOTINIB | 393.44 | C22H23N3O4 | NEUTRAL | Details |
| B014805 | CHEMBL554 | Small molecule | LAPATINIB | 581.07 | C29H26ClFN4O4S | NEUTRAL | Details |
| B019081 | CHEMBL278041 | Small molecule | SB-202190 | 331.35 | C20H14FN3O | NEUTRAL | Details |
| B033576 | CHEMBL24828 | Small molecule | VANDETANIB | 475.36 | C22H24BrFN4O2 | BASE | Details |
| B041764 | CHEMBL31965 | Small molecule | CANERTINIB | 485.95 | C24H25ClFN5O3 | NEUTRAL | Details |
| Article ID | PMID | Source | Title |
|---|