Therapeutic Target Details
| Target ID: | T22 |
| Target Name: | Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 |
| Synonyms: | M6S1; NPPS; PC1; PDNP1; Synonyms=M6S1; PC1 GN ; Ectonucleotide pyrophosphatase/phosphodiesterase family member 1; Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, secreted form; Alkaline phosphodiesterase I; Membrane component chromosome 6 surface marker 1; Nucleotide diphosphatase; Nucleotide pyrophosphatase; Phosphodiesterase I/nucleotide pyrophosphatase 1; Plasma-cell membrane glycoprotein PC-1; E-NPP 1; NPPase; 3.1.4.1; 3.6.1.9 |
| GENE: | ENPP1 |
| Action: | |
| Class: | Target is a single protein chain |
| UniProtKB ID: | P22413 |
| Entry Name: | ENPP1_HUMAN |
| Related Drugs: | |
| Mechanism: | |
| Reference (PMIDs): |
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress |
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| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria |
|---|
| Compound ID | Source ID | Source Type | Compound Name | Molecular Weight | Molecular Formula | Molecular Species | |
|---|---|---|---|---|---|---|---|
| B066277 | CHEMBL298036 | Small molecule | 201.23 | C11H11N3O | NEUTRAL | Details | |
| B112098 | CHEMBL69234 | Small molecule | 511.38 | C14H14N3O12PS2 | ACID | Details | |
| B217883 | CHEMBL132722 | Small molecule | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER | 505.21 | C11H18N5O12P3 | ACID | Details |
| B217939 | CHEMBL435402 | Small molecule | 473.3 | C11H17N5O10P2S | ACID | Details | |
| B217942 | CHEMBL336208 | Small molecule | 553.28 | C11H18N5O13P3S | ACID | Details | |
| B389593 | CHEMBL243638 | Small molecule | 269.13 | C12H10Cl2N2O | NEUTRAL | Details | |
| B389604 | CHEMBL390695 | Small molecule | 234.69 | C12H11ClN2O | NEUTRAL | Details | |
| B570665 | CHEMBL583969 | Small molecule | PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER | 425.23 | C11H17N5O9P2 | ACID | Details |
| B588451 | CHEMBL579992 | Small molecule | 312.78 | C16H9ClN2OS | NEUTRAL | Details | |
| B592137 | CHEMBL607528 | Small molecule | 284.34 | C15H12N2O2S | ACID | Details |
| Article ID | PMID | Source | Title |
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