Therapeutic Target Details
| Target ID: | T35 |
| Target Name: | Sphingosine-1-phosphate lyase 1 |
| Synonyms: | Synonyms=KIAA1252; Sphingosine-1-phosphate lyase 1; Sphingosine-1-phosphate aldolase; S1PL; SP-lyase 1; SPL 1; hSPL; 4.1.2.27 |
| GENE: | SGPL1 |
| Action: | |
| Class: | Lyase |
| UniProtKB ID: | O95470 |
| Entry Name: | SGPL1_HUMAN |
| Related Drugs: | |
| Mechanism: | |
| Reference (PMIDs): |
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress |
|---|
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria |
|---|
| Compound ID | Source ID | Source Type | Compound Name | Molecular Weight | Molecular Formula | Molecular Species | |
|---|---|---|---|---|---|---|---|
| B144940 | CHEMBL314854 | Small molecule | FINGOLIMOD | 307.48 | C19H33NO2 | BASE | Details |
| B500054 | CHEMBL491458 | Small molecule | 528.62 | C28H32N8O3 | NEUTRAL | Details | |
| B500055 | CHEMBL488336 | Small molecule | 230.22 | C9H14N2O5 | NEUTRAL | Details | |
| B501259 | CHEMBL497436 | Small molecule | 420.52 | C26H24N6 | NEUTRAL | Details | |
| B501260 | CHEMBL497437 | Small molecule | 420.52 | C26H24N6 | NEUTRAL | Details | |
| B501961 | CHEMBL497534 | Small molecule | 406.49 | C25H22N6 | NEUTRAL | Details | |
| B1192843 | CHEMBL1852164 | Small molecule | LX-2931 | 245.24 | C9H15N3O5 | NEUTRAL | Details |
| B1760876 | CHEMBL3290320 | Small molecule | 467.57 | C28H29N5O2 | NEUTRAL | Details | |
| B1760877 | CHEMBL3290321 | Small molecule | 463.51 | C26H24F3N5 | NEUTRAL | Details | |
| B1760878 | CHEMBL3290322 | Small molecule | 440.51 | C25H24N6O2 | NEUTRAL | Details |
| Article ID | PMID | Source | Title |
|---|